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The role of Purkinje cell-derived VEGF in cerebellar astrogliosis in Niemann-Pick type C mice

Niemann-Pick type C disease (NP-C) is a fatal neuro-degenerative disorder caused by a deficiency of NPC1 gene function, which leads to severe neuroinflammation such as astrogliosis. While reports demonstrating neuroinflammation are prevalent in NP-C, information about the onset and progression of ce...

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Detalles Bibliográficos
Autores principales: Park, Min Hee, Lee, Ju Youn, Jeong, Min Seock, Jang, Hyung Sup, Endo, Shogo, Bae, Jae-sung, Jin, Hee Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836561/
https://www.ncbi.nlm.nih.gov/pubmed/29397865
http://dx.doi.org/10.5483/BMBRep.2018.51.2.168