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Adequate concentration of B cell leukemia/lymphoma 3 (Bcl3) is required for pluripotency and self-renewal of mouse embryonic stem cells via downregulation of Nanog transcription

B cell leukemia/lymphoma 3 (Bcl3) plays a pivotal role in immune homeostasis, cellular proliferation, and cell survival, as a co-activator or co-repressor of transcription of the NF-κB family. Recently, it was reported that Bcl3 positively regulates pluripotency genes, including Oct4, in mouse embry...

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Detalles Bibliográficos
Autores principales: Kang, Songhwa, Yun, Jisoo, Kim, Da Yeon, Jung, Seok Yun, Kim, Yeon Ju, Park, Ji Hye, Ji, Seung Taek, Jang, Woong Bi, Ha, Jongseong, Kim, Jae Ho, Baek, Sang Hong, Kwon, Sang-Mo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836563/
https://www.ncbi.nlm.nih.gov/pubmed/29335071
http://dx.doi.org/10.5483/BMBRep.2018.51.2.219