Mutations in the gyrA, parC, and mexR genes provide functional insights into the fluoroquinolone-resistant Pseudomonas aeruginosa isolated in Vietnam

INTRODUCTION: Pseudomonas aeruginosa has many mechanisms of resistance to fluoroquinolones. The main mechanism is to change the effect of two enzymes that open the DNA helix – the enzyme DNA gyrase (gyrA) and the topoisomerase IV (parC). In addition, mutations that render the MexAB-oprM pump (mexR)...

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Detalles Bibliográficos
Autores principales: Nguyen, Kinh Van, Nguyen, Trung Vu, Nguyen, Hang Thi Thuy, Le, Duyet Van
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836672/
https://www.ncbi.nlm.nih.gov/pubmed/29535543
http://dx.doi.org/10.2147/IDR.S147581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836672/
https://www.ncbi.nlm.nih.gov/pubmed/29535543
http://dx.doi.org/10.2147/IDR.S147581

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