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Innate immunity mediated by dendritic cells/macrophages plays a central role in the early period in tumor treatment using gene of Mycobacterium tuberculosis antigen

By using a complex of DNA, polyethylenimine and chondroitin sulfate, the in vivo transfection of early secretory antigenic target-6 (ESAT-6) gene into tumor cells was found to cause significant suppression of the tumor growth. In order to apply the method in clinical cancer treatment in dogs and cat...

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Detalles Bibliográficos
Autores principales: USHIGUSA, Takahiro, KOYAMA, Yoshiyuki, ITO, Tomoko, WATANABE, Kenichi, CHAMBERS, James K., HASEGAWA, Aya, UCHIDA, Kazuyuki, KANEGI, Ryoji, HATOYA, Shingo, INABA, Toshio, SUGIURA, Kikuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836752/
https://www.ncbi.nlm.nih.gov/pubmed/29311492
http://dx.doi.org/10.1292/jvms.17-0466