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Innate immunity mediated by dendritic cells/macrophages plays a central role in the early period in tumor treatment using gene of Mycobacterium tuberculosis antigen
By using a complex of DNA, polyethylenimine and chondroitin sulfate, the in vivo transfection of early secretory antigenic target-6 (ESAT-6) gene into tumor cells was found to cause significant suppression of the tumor growth. In order to apply the method in clinical cancer treatment in dogs and cat...
Autores principales: | USHIGUSA, Takahiro, KOYAMA, Yoshiyuki, ITO, Tomoko, WATANABE, Kenichi, CHAMBERS, James K., HASEGAWA, Aya, UCHIDA, Kazuyuki, KANEGI, Ryoji, HATOYA, Shingo, INABA, Toshio, SUGIURA, Kikuya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Veterinary Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836752/ https://www.ncbi.nlm.nih.gov/pubmed/29311492 http://dx.doi.org/10.1292/jvms.17-0466 |
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