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Drug Repurposing by Simulating Flow Through Protein–Protein Interaction Networks

As drug development is extremely expensive, the identification of novel indications for in‐market drugs is financially attractive. Multiple algorithms are used to support such drug repurposing, but highly reliable methods combining simulation of intracellular networks and machine learning are curren...

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Detalles Bibliográficos
Autores principales: Manczinger, M, Bodnár, VÁ, Papp, BT, Bolla, SB, Szabó, K, Balázs, B, Csányi, E, Szél, E, Erős, G, Kemény, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836852/
https://www.ncbi.nlm.nih.gov/pubmed/28643328
http://dx.doi.org/10.1002/cpt.769