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BAFF augments IgA2 and IL‐10 production by TLR7/8 stimulated total peripheral blood B cells

Class‐switching of B cells to IgA can be induced via both T‐cell‐dependent and T‐cell‐independent mechanisms. IgA is most predominantly produced mucosally and is important for combating infections and allergies. In contrast to mice, humans have two forms of IgA; IgA1 and IgA2 with diverse tissue dis...

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Detalles Bibliográficos
Autores principales: den Hartog, Gerco, van Osch, Thijs L.J., Vos, Martijn, Meijer, Ben, Savelkoul, Huub F.J., van Neerven, R.J. Joost, Brugman, Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836859/
https://www.ncbi.nlm.nih.gov/pubmed/28921509
http://dx.doi.org/10.1002/eji.201646861