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BAFF augments IgA2 and IL‐10 production by TLR7/8 stimulated total peripheral blood B cells
Class‐switching of B cells to IgA can be induced via both T‐cell‐dependent and T‐cell‐independent mechanisms. IgA is most predominantly produced mucosally and is important for combating infections and allergies. In contrast to mice, humans have two forms of IgA; IgA1 and IgA2 with diverse tissue dis...
Autores principales: | den Hartog, Gerco, van Osch, Thijs L.J., Vos, Martijn, Meijer, Ben, Savelkoul, Huub F.J., van Neerven, R.J. Joost, Brugman, Sylvia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836859/ https://www.ncbi.nlm.nih.gov/pubmed/28921509 http://dx.doi.org/10.1002/eji.201646861 |
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