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TMEFF2 shedding is regulated by oxidative stress and mediated by ADAMs and transmembrane serine proteases implicated in prostate cancer

TMEFF2 is a type I transmembrane protein with two follistatin (FS) and one EGF‐like domain over‐expressed in prostate cancer; however its biological role in prostate cancer development and progression remains unclear, which may, at least in part, be explained by its proteolytic processing. The extra...

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Detalles Bibliográficos
Autores principales: Gaweł‐Bęben, Katarzyna, Ali, Nazim, Ellis, Vincent, Velasco, Gloria, Poghosyan, Zaruhi, Ager, Ann, Knäuper, Vera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836882/
https://www.ncbi.nlm.nih.gov/pubmed/28762604
http://dx.doi.org/10.1002/cbin.10832