Ursodeoxycholic acid: Effects on hepatic unfolded protein response, apoptosis and oxidative stress in morbidly obese patients

BACKGROUND & AIMS: Ursodeoxycholic acid (UDCA) is a secondary hydrophilic bile acid (BA) used as therapy for a range of hepatobiliary diseases. Its efficacy in non‐alcoholic fatty liver disease (NAFLD) is still under debate. Here, we aimed to decipher molecular mechanisms of UDCA in regulating e...

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Detalles Bibliográficos
Autores principales: Mueller, Michaela, Castro, Rui E., Thorell, Anders, Marschall, Hanns‐Ulrich, Auer, Nicole, Herac, Merima, Rodrigues, Cecilia M.P., Trauner, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Genetic and Metabolic Liver Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836915/
https://www.ncbi.nlm.nih.gov/pubmed/28853202
http://dx.doi.org/10.1111/liv.13562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836915/
https://www.ncbi.nlm.nih.gov/pubmed/28853202
http://dx.doi.org/10.1111/liv.13562

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