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Evolutionary conservation of DNA methylation in CpG sites within ultraconserved noncoding elements

Ultraconserved noncoding elements (UCNEs) constitute less than 1 Mb of vertebrate genomes and are impervious to accumulating mutations. About 4000 UCNEs exist in vertebrate genomes, each at least 200 nucleotides in length, sharing greater than 95% sequence identity between human and chicken. Despite...

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Detalles Bibliográficos
Autores principales: Colwell, Mathia, Drown, Melissa, Showel, Kelly, Drown, Chelsea, Palowski, Amanda, Faulk, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836973/
https://www.ncbi.nlm.nih.gov/pubmed/29372669
http://dx.doi.org/10.1080/15592294.2017.1411447