Development of a multiple-gene-loading method by combining multi-integration system-equipped mouse artificial chromosome vector and CRISPR-Cas9

Mouse artificial chromosome (MAC) vectors have several advantages as gene delivery vectors, such as stable and independent maintenance in host cells without integration, transferability from donor cells to recipient cells via microcell-mediated chromosome transfer (MMCT), and the potential for loadi...

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Detalles Bibliográficos
Autores principales: Honma, Kazuhisa, Abe, Satoshi, Endo, Takeshi, Uno, Narumi, Oshimura, Mitsuo, Ohbayashi, Tetsuya, Kazuki, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837097/
https://www.ncbi.nlm.nih.gov/pubmed/29505588
http://dx.doi.org/10.1371/journal.pone.0193642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837097/
https://www.ncbi.nlm.nih.gov/pubmed/29505588
http://dx.doi.org/10.1371/journal.pone.0193642

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