Cargando…

Development of a multiple-gene-loading method by combining multi-integration system-equipped mouse artificial chromosome vector and CRISPR-Cas9

Mouse artificial chromosome (MAC) vectors have several advantages as gene delivery vectors, such as stable and independent maintenance in host cells without integration, transferability from donor cells to recipient cells via microcell-mediated chromosome transfer (MMCT), and the potential for loadi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Honma, Kazuhisa, Abe, Satoshi, Endo, Takeshi, Uno, Narumi, Oshimura, Mitsuo, Ohbayashi, Tetsuya, Kazuki, Yasuhiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837097/ https://www.ncbi.nlm.nih.gov/pubmed/29505588 http://dx.doi.org/10.1371/journal.pone.0193642

Ejemplares similares

CRISPR/Cas9-induced transgene insertion and telomere-associated truncation of a single human chromosome for chromosome engineering in CHO and A9 cells
por: Uno, Narumi, et al.
Publicado: (2017)

A Method for Producing Transgenic Cells Using a Multi-Integrase System on a Human Artificial Chromosome Vector
por: Yamaguchi, Shigeyuki, et al.
Publicado: (2011)

A pathway from chromosome transfer to engineering resulting in human and mouse artificial chromosomes for a variety of applications to bio-medical challenges
por: Oshimura, Mitsuo, et al.
Publicado: (2015)

Mouse embryonic stem cells with a multi-integrase mouse artificial chromosome for transchromosomic mouse generation
por: Yoshimura, Yuki, et al.
Publicado: (2015)

A kidney injury molecule‐1 (Kim‐1) gene reporter in a mouse artificial chromosome: the responsiveness to cisplatin toxicity in immortalized mouse kidney S3 cells
por: Kokura, Kenji, et al.
Publicado: (2016)

Construction of stable mouse artificial chromosome from native mouse chromosome 10 for generation of transchromosomic mice
por: Abe, Satoshi, et al.
Publicado: (2021)

An efficient protein production system via gene amplification on a human artificial chromosome and the chromosome transfer to CHO cells
por: Ohira, Takahito, et al.
Publicado: (2019)

Development of a Safeguard System Using an Episomal Mammalian Artificial Chromosome for Gene and Cell Therapy
por: Uno, Narumi, et al.
Publicado: (2015)

Integration-Free iPS Cells Engineered Using Human Artificial Chromosome Vectors
por: Hiratsuka, Masaharu, et al.
Publicado: (2011)

Transfer of a Mouse Artificial Chromosome into Spermatogonial Stem Cells Generates Transchromosomic Mice
por: Shinohara, Takashi, et al.
Publicado: (2017)

Multiple expression cassette exchange via TP901‐1, R4, and Bxb1 integrase systems on a mouse artificial chromosome
por: Tomimatsu, Kosuke, et al.
Publicado: (2017)

A luciferase complementation assay system using transferable mouse artificial chromosomes to monitor protein–protein interactions mediated by G protein-coupled receptors
por: Uno, Narumi, et al.
Publicado: (2018)

Treatment of CHO cells with Taxol and reversine improves micronucleation and microcell-mediated chromosome transfer efficiency
por: Uno, Narumi, et al.
Publicado: (2023)

A Novel System for Simultaneous or Sequential Integration of Multiple Gene-Loading Vectors into a Defined Site of a Human Artificial Chromosome
por: Suzuki, Teruhiko, et al.
Publicado: (2014)

Use of a Human Artificial Chromosome for Delivering Trophic Factors in a Rodent Model of Amyotrophic Lateral Sclerosis
por: Watanabe, Yasuhiro, et al.
Publicado: (2015)

A Human Artificial Chromosome Recapitulates the Metabolism of Native Telomeres in Mammalian Cells
por: Wakai, Michihito, et al.
Publicado: (2014)

Retargeting of microcell fusion towards recipient cell-oriented transfer of human artificial chromosome
por: Hiratsuka, Masaharu, et al.
Publicado: (2015)

Development of Caco-2 cells expressing four CYPs via a mammalian artificial chromosome
por: Ohta, Yumi, et al.
Publicado: (2020)

Panel of human cell lines with human/mouse artificial chromosomes
por: Uno, Narumi, et al.
Publicado: (2022)

Engineering of human induced pluripotent stem cells via human artificial chromosome vectors for cell therapy and disease modeling
por: Kazuki, Yasuhiro, et al.
Publicado: (2020)

Full-length human dystrophin on human artificial chromosome compensates for mouse dystrophin deficiency in a Duchenne muscular dystrophy mouse model
por: Hiramuki, Yosuke, et al.
Publicado: (2023)

Establishment of a novel hepatocyte model that expresses four cytochrome P450 genes stably via mammalian-derived artificial chromosome for pharmacokinetics and toxicity studies
por: Satoh, Daisuke, et al.
Publicado: (2017)

Simultaneous loading of PCR-based multiple fragments on mouse artificial chromosome vectors in DT40 cell for gene delivery
por: Yamazaki, Kyotaro, et al.
Publicado: (2022)

Publisher Correction: Simultaneous loading of PCR-based multiple fragments on mouse artificial chromosome vectors in DT40 cell for gene delivery
por: Yamazaki, Kyotaro, et al.
Publicado: (2023)

Down syndrome-associated haematopoiesis abnormalities created by chromosome transfer and genome editing technologies
por: Kazuki, Yasuhiro, et al.
Publicado: (2014)

Complete restoration of multiple dystrophin isoforms in genetically corrected Duchenne muscular dystrophy patient–derived cardiomyocytes
por: Zatti, Susi, et al.
Publicado: (2014)

Refined human artificial chromosome vectors for gene therapy and animal transgenesis
por: Kazuki, Y, et al.
Publicado: (2011)

Dual-Color Fluorescence Imaging to Monitor CYP3A4 and CYP3A7 Expression in Human Hepatic Carcinoma HepG2 and HepaRG Cells
por: Tsuji, Saori, et al.
Publicado: (2014)

Reversible immortalisation enables genetic correction of human muscle progenitors and engineering of next‐generation human artificial chromosomes for Duchenne muscular dystrophy
por: Benedetti, Sara, et al.
Publicado: (2017)

Highly Efficient Transfer of Chromosomes to a Broad Range of Target Cells Using Chinese Hamster Ovary Cells Expressing Murine Leukemia Virus-Derived Envelope Proteins
por: Suzuki, Teruhiko, et al.
Publicado: (2016)

A Cytoplasmic Form of Gaussia luciferase Provides a Highly Sensitive Test for Cytotoxicity
por: Tsuji, Saori, et al.
Publicado: (2016)

Analysis of in vitro and in vivo metabolism of zidovudine and gemfibrozil in trans‐chromosomic mouse line expressing human UGT2 enzymes
por: Kobayashi, Kaoru, et al.
Publicado: (2022)

Bioluminescence Measurement of Time-Dependent Dynamic Changes of CYP-Mediated Cytotoxicity in CYP-Expressing Luminescent HepG2 Cells
por: Iwado, Satoru, et al.
Publicado: (2021)

Human Artificial Chromosome with a Conditional Centromere for Gene Delivery and Gene Expression
por: Iida, Yuichi, et al.
Publicado: (2010)

Exploitation of the interaction of measles virus fusogenic envelope proteins with the surface receptor CD46 on human cells for microcell-mediated chromosome transfer
por: Katoh, Motonobu, et al.
Publicado: (2010)

Chromosome engineering in zygotes with CRISPR/Cas9
por: Boroviak, Katharina, et al.
Publicado: (2016)

Reshuffling yeast chromosomes with CRISPR/Cas9
por: Fleiss, Aubin, et al.
Publicado: (2019)

Modification of single-nucleotide polymorphism in a fully humanized CYP3A mouse by genome editing technology
por: Abe, Satoshi, et al.
Publicado: (2017)

Studies of Tumor Suppressor Genes via Chromosome Engineering
por: Kugoh, Hiroyuki, et al.
Publicado: (2015)

Dysregulation of Gene Expression in the Artificial Human Trisomy Cells of Chromosome 8 Associated with Transformed Cell Phenotypes
por: Nawata, Hisakatsu, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_3gqatifbbsg5oc9dcc1m3mq0qp