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Tolvaptan suppresses monocyte chemotactic protein-1 excretion in autosomal-dominant polycystic kidney disease

Background: Autosomal-dominant polycystic kidney disease (ADPKD) is characterized by multitudes of expanding renal cysts associated with mononuclear interstitial infiltrates. Monocyte chemotactic protein-1 is produced in the kidneys and excreted in the urine (uMCP1) of these patients in increased am...

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Detalles Bibliográficos
Autores principales: Grantham, Jared J., Chapman, Arlene B., Blais, Jaime, Czerwiec, Frank S., Devuyst, Olivier, Gansevoort, Ron T., Higashihara, Eiji, Krasa, Holly, Zhou, Wen, Ouyang, John, Perrone, Ronald D., Torres, Vicente E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837351/
https://www.ncbi.nlm.nih.gov/pubmed/27190355
http://dx.doi.org/10.1093/ndt/gfw060