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Tolvaptan suppresses monocyte chemotactic protein-1 excretion in autosomal-dominant polycystic kidney disease
Background: Autosomal-dominant polycystic kidney disease (ADPKD) is characterized by multitudes of expanding renal cysts associated with mononuclear interstitial infiltrates. Monocyte chemotactic protein-1 is produced in the kidneys and excreted in the urine (uMCP1) of these patients in increased am...
Autores principales: | Grantham, Jared J., Chapman, Arlene B., Blais, Jaime, Czerwiec, Frank S., Devuyst, Olivier, Gansevoort, Ron T., Higashihara, Eiji, Krasa, Holly, Zhou, Wen, Ouyang, John, Perrone, Ronald D., Torres, Vicente E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837351/ https://www.ncbi.nlm.nih.gov/pubmed/27190355 http://dx.doi.org/10.1093/ndt/gfw060 |
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