Defining the genetic architecture of hypertrophic cardiomyopathy: re-evaluating the role of non-sarcomeric genes

AIM: Hypertrophic cardiomyopathy (HCM) exhibits genetic heterogeneity that is dominated by variation in eight sarcomeric genes. Genetic variation in a large number of non-sarcomeric genes has also been implicated in HCM but not formally assessed. Here we used very large case and control cohorts to d...

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Detalles Bibliográficos
Autores principales: Walsh, Roddy, Buchan, Rachel, Wilk, Alicja, John, Shibu, Felkin, Leanne E, Thomson, Kate L, Chiaw, Tang Hak, Loong, Calvin Chin Woon, Pua, Chee Jian, Raphael, Claire, Prasad, Sanjay, Barton, Paul J, Funke, Birgit, Watkins, Hugh, Ware, James S, Cook, Stuart A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837460/
https://www.ncbi.nlm.nih.gov/pubmed/28082330
http://dx.doi.org/10.1093/eurheartj/ehw603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837460/
https://www.ncbi.nlm.nih.gov/pubmed/28082330
http://dx.doi.org/10.1093/eurheartj/ehw603

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