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Mendelian randomization: a novel approach for the prediction of adverse drug events and drug repurposing opportunities

Identification of unintended drug effects, specifically drug repurposing opportunities and adverse drug events, maximizes the benefit of a drug and protects the health of patients. However, current observational research methods are subject to several biases. These include confounding by indication,...

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Detalles Bibliográficos
Autores principales: Walker, Venexia M, Davey Smith, George, Davies, Neil M, Martin, Richard M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837479/
https://www.ncbi.nlm.nih.gov/pubmed/29040597
http://dx.doi.org/10.1093/ije/dyx207