Differential effects of PCSK9 variants on risk of coronary disease and ischaemic stroke

AIMS: PCSK9 genetic variants that have large effects on low-density lipoprotein cholesterol (LDL-C) and coronary heart disease (CHD) have prompted the development of therapeutic PCSK9-inhibition. However, there is limited evidence that PCSK9 variants are associated with ischaemic stroke (IS). METHOD...

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Detalles Bibliográficos
Autores principales: Hopewell, Jemma C, Malik, Rainer, Valdés-Márquez, Elsa, Worrall, Bradford B, Collins, Rory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Fast Track Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837489/
https://www.ncbi.nlm.nih.gov/pubmed/29020353
http://dx.doi.org/10.1093/eurheartj/ehx373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837489/
https://www.ncbi.nlm.nih.gov/pubmed/29020353
http://dx.doi.org/10.1093/eurheartj/ehx373

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