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Multiple sclerosis risk variants alter expression of co-stimulatory genes in B cells

The increasing evidence supporting a role for B cells in the pathogenesis of multiple sclerosis prompted us to investigate the influence of known susceptibility variants on the surface expression of co-stimulatory molecules in these cells. Using flow cytometry we measured surface expression of CD40...

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Detalles Bibliográficos
Autores principales: Smets, Ide, Fiddes, Barnaby, Garcia-Perez, Josselyn E, He, Di, Mallants, Klara, Liao, Wenjia, Dooley, James, Wang, George, Humblet-Baron, Stephanie, Dubois, Bénédicte, Compston, Alastair, Jones, Joanne, Coles, Alasdair, Liston, Adrian, Ban, Maria, Goris, An, Sawcer, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837558/
https://www.ncbi.nlm.nih.gov/pubmed/29361022
http://dx.doi.org/10.1093/brain/awx372