Efficient termination of nuclear lncRNA transcription promotes mitochondrial genome maintenance

Most DNA in the genomes of higher organisms does not code for proteins. RNA Polymerase II (Pol II) transcribes non-coding DNA into long non-coding RNAs (lncRNAs), but biological roles of lncRNA are unclear. We find that mutations in the yeast lncRNA CUT60 result in poor growth. Defective termination...

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Detalles Bibliográficos
Autores principales: du Mee, Dorine Jeanne Mariëtte, Ivanov, Maxim, Parker, Joseph Paul, Buratowski, Stephen, Marquardt, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837560/
https://www.ncbi.nlm.nih.gov/pubmed/29504936
http://dx.doi.org/10.7554/eLife.31989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837560/
https://www.ncbi.nlm.nih.gov/pubmed/29504936
http://dx.doi.org/10.7554/eLife.31989

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