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CdGAP/ARHGAP31 is regulated by RSK phosphorylation and binding to 14-3-3β adaptor protein

Cdc42 GTPase-activating protein (CdGAP, also named ARHGAP31) is a negative regulator of the GTPases Rac1 and Cdc42. Associated with the rare developmental disorder Adams-Oliver Syndrome (AOS), CdGAP is critical for embryonic vascular development and VEGF-mediated angiogenesis. Moreover, CdGAP is an...

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Detalles Bibliográficos
Autores principales: Ben Djoudi Ouadda, Ali, He, Yi, Calabrese, Viviane, Ishii, Hidetaka, Chidiac, Rony, Gratton, Jean-Philippe, Roux, Philippe P., Lamarche-Vane, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837747/
https://www.ncbi.nlm.nih.gov/pubmed/29545927
http://dx.doi.org/10.18632/oncotarget.24126