Cargando…
HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease
Peripheral nerve axons require a well-organized axonal microtubule network for efficient transport to ensure the constant crosstalk between soma and synapse. Mutations in more than 80 different genes cause Charcot-Marie-Tooth disease, which is the most common inherited disorder affecting peripheral...
Autores principales: | , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837793/ https://www.ncbi.nlm.nih.gov/pubmed/29415205 http://dx.doi.org/10.1093/brain/awx375 |