HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease

Peripheral nerve axons require a well-organized axonal microtubule network for efficient transport to ensure the constant crosstalk between soma and synapse. Mutations in more than 80 different genes cause Charcot-Marie-Tooth disease, which is the most common inherited disorder affecting peripheral...

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Detalles Bibliográficos
Autores principales: Benoy, Veronick, Van Helleputte, Lawrence, Prior, Robert, d’Ydewalle, Constantin, Haeck, Wanda, Geens, Natasja, Scheveneels, Wendy, Schevenels, Begga, Cader, M Zameel, Talbot, Kevin, Kozikowski, Alan P, Vanden Berghe, Pieter, Van Damme, Philip, Robberecht, Wim, Van Den Bosch, Ludo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837793/
https://www.ncbi.nlm.nih.gov/pubmed/29415205
http://dx.doi.org/10.1093/brain/awx375

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