LRRK2 Contributes to Secondary Brain Injury Through a p38/Drosha Signaling Pathway After Traumatic Brain Injury in Rats

Leucine-rich repeat kinase 2 (LRRK2) is widely expressed in the brain and exerts neurotoxicity in Parkinson’s disease. The p38/Drosha signaling activation has been reported to increase cell death under stress. This study was designed to investigate the potential role and mechanism of LRRK2 in second...

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Detalles Bibliográficos
Autores principales: Rui, Qin, Ni, Haibo, Gao, Fan, Dang, Baoqi, Li, Di, Gao, Rong, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837969/
https://www.ncbi.nlm.nih.gov/pubmed/29545743
http://dx.doi.org/10.3389/fncel.2018.00051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837969/
https://www.ncbi.nlm.nih.gov/pubmed/29545743
http://dx.doi.org/10.3389/fncel.2018.00051

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