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Maternal 5(m)CpG Imprints at the PARD6G-AS1 and GCSAML Differentially Methylated Regions Are Decoupled From Parent-of-Origin Expression Effects in Multiple Human Tissues

A hallmark of imprinted genes in mammals is the occurrence of parent-of-origin-dependent asymmetry of DNA cytosine methylation (5(m)C) of alleles at CpG islands (CGIs) in their promoter regions. This 5(m)CpG asymmetry between the parental alleles creates allele-specific imprinted differentially meth...

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Detalles Bibliográficos
Autores principales: de Sá Machado Araújo, Graziela, da Silva Francisco Junior, Ronaldo, dos Santos Ferreira, Cristina, Mozer Rodrigues, Pedro Thyago, Terra Machado, Douglas, Louvain de Souza, Thais, Teixeira de Souza, Jozimara, Figueiredo Osorio da Silva, Cleiton, Alves da Silva, Antônio Francisco, Andrade, Claudia Caixeta Franco, da Silva, Alan Tardin, Ramos, Victor, Garcia, Ana Beatriz, Machado, Filipe Brum, Medina-Acosta, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838017/
https://www.ncbi.nlm.nih.gov/pubmed/29545821
http://dx.doi.org/10.3389/fgene.2018.00036