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Maternal 5(m)CpG Imprints at the PARD6G-AS1 and GCSAML Differentially Methylated Regions Are Decoupled From Parent-of-Origin Expression Effects in Multiple Human Tissues
A hallmark of imprinted genes in mammals is the occurrence of parent-of-origin-dependent asymmetry of DNA cytosine methylation (5(m)C) of alleles at CpG islands (CGIs) in their promoter regions. This 5(m)CpG asymmetry between the parental alleles creates allele-specific imprinted differentially meth...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838017/ https://www.ncbi.nlm.nih.gov/pubmed/29545821 http://dx.doi.org/10.3389/fgene.2018.00036 |