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Insulin-signalling dysregulation and inflammation is programmed trans-generationally in a female rat model of poor maternal nutrition

Developmental programming phenotypes can be recapitulated in subsequent generations not directly exposed to the initial suboptimal intrauterine environment. A maternal low-protein diet during pregnancy and postnatal catch-up growth (‘recuperated’) alters insulin signaling and inflammation in rat off...

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Detalles Bibliográficos
Autores principales: Tarry-Adkins, Jane L., Aiken, Catherine E., Ashmore, Thomas J., Ozanne, Susan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838091/
https://www.ncbi.nlm.nih.gov/pubmed/29507362
http://dx.doi.org/10.1038/s41598-018-22383-w