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Insulin-signalling dysregulation and inflammation is programmed trans-generationally in a female rat model of poor maternal nutrition
Developmental programming phenotypes can be recapitulated in subsequent generations not directly exposed to the initial suboptimal intrauterine environment. A maternal low-protein diet during pregnancy and postnatal catch-up growth (‘recuperated’) alters insulin signaling and inflammation in rat off...
Autores principales: | Tarry-Adkins, Jane L., Aiken, Catherine E., Ashmore, Thomas J., Ozanne, Susan E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838091/ https://www.ncbi.nlm.nih.gov/pubmed/29507362 http://dx.doi.org/10.1038/s41598-018-22383-w |
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