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Periostin blockade overcomes chemoresistance via restricting the expansion of mesenchymal tumor subpopulations in breast cancer

Recent studies suggest a functional involvement of Epithelial-Mesenchymal Transition (EMT) in tumor chemoresistance. Specifically, EMT is associated with chemoresistance and poor prognosis in triple-negative breast cancer. However, no effective therapy targeting EMT has been developed. Here, we repo...

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Detalles Bibliográficos
Autores principales: Nakazawa, Youya, Taniyama, Yoshiaki, Sanada, Fumihiro, Morishita, Ryuichi, Nakamori, Shoji, Morimoto, Koji, Yeung, Kay T., Yang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838092/
https://www.ncbi.nlm.nih.gov/pubmed/29507310
http://dx.doi.org/10.1038/s41598-018-22340-7