Cancer-associated fibroblasts induce antigen-specific deletion of CD8(+) T Cells to protect tumour cells

Tumours have developed strategies to interfere with most steps required for anti-tumour immune responses. Although many populations contribute to anti-tumour responses, tumour-infiltrating cytotoxic T cells dominate, hence, many suppressive strategies act to inhibit these. Tumour-associated T cells...

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Detalles Bibliográficos
Autores principales: Lakins, Matthew A., Ghorani, Ehsan, Munir, Hafsa, Martins, Carla P., Shields, Jacqueline D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838096/
https://www.ncbi.nlm.nih.gov/pubmed/29507342
http://dx.doi.org/10.1038/s41467-018-03347-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838096/
https://www.ncbi.nlm.nih.gov/pubmed/29507342
http://dx.doi.org/10.1038/s41467-018-03347-0

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