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Cancer-associated fibroblasts induce antigen-specific deletion of CD8(+) T Cells to protect tumour cells
Tumours have developed strategies to interfere with most steps required for anti-tumour immune responses. Although many populations contribute to anti-tumour responses, tumour-infiltrating cytotoxic T cells dominate, hence, many suppressive strategies act to inhibit these. Tumour-associated T cells...
Autores principales: | Lakins, Matthew A., Ghorani, Ehsan, Munir, Hafsa, Martins, Carla P., Shields, Jacqueline D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838096/ https://www.ncbi.nlm.nih.gov/pubmed/29507342 http://dx.doi.org/10.1038/s41467-018-03347-0 |
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