Microhomology-assisted scarless genome editing in human iPSCs

Gene-edited induced pluripotent stem cells (iPSCs) provide relevant isogenic human disease models in patient-specific or healthy genetic backgrounds. Towards this end, gene targeting using antibiotic selection along with engineered point mutations remains a reliable method to enrich edited cells. Ne...

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Detalles Bibliográficos
Autores principales: Kim, Shin-Il, Matsumoto, Tomoko, Kagawa, Harunobu, Nakamura, Michiko, Hirohata, Ryoko, Ueno, Ayano, Ohishi, Maki, Sakuma, Tetsushi, Soga, Tomoyoshi, Yamamoto, Takashi, Woltjen, Knut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838097/
https://www.ncbi.nlm.nih.gov/pubmed/29507284
http://dx.doi.org/10.1038/s41467-018-03044-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838097/
https://www.ncbi.nlm.nih.gov/pubmed/29507284
http://dx.doi.org/10.1038/s41467-018-03044-y

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