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Modulation of Oral Bioavailability and Metabolism for Closely Related Cyclic Hexapeptides
ABSTRACT: Recently, a variety of studies concerned with the permeability and oral bioavailability of cyclic peptides have been reported. In particular, strategies aiming at modifying peptides to maintain or to enhance solubility while enabling permeability constitute a significant challenge, but are...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838147/ https://www.ncbi.nlm.nih.gov/pubmed/29527142 http://dx.doi.org/10.1007/s10989-017-9590-8 |