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Modulation of Oral Bioavailability and Metabolism for Closely Related Cyclic Hexapeptides

ABSTRACT: Recently, a variety of studies concerned with the permeability and oral bioavailability of cyclic peptides have been reported. In particular, strategies aiming at modifying peptides to maintain or to enhance solubility while enabling permeability constitute a significant challenge, but are...

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Detalles Bibliográficos
Autores principales:	Vorherr, Thomas, Lewis, Ian, Berghausen, Joerg, Desrayaud, Sandrine, Schaefer, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838147/ https://www.ncbi.nlm.nih.gov/pubmed/29527142 http://dx.doi.org/10.1007/s10989-017-9590-8

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