Dissecting super-enhancer hierarchy based on chromatin interactions

Recent studies have highlighted super-enhancers (SEs) as important regulatory elements for gene expression, but their intrinsic properties remain incompletely characterized. Through an integrative analysis of Hi-C and ChIP-seq data, here we find that a significant fraction of SEs are hierarchically...

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Detalles Bibliográficos
Autores principales: Huang, Jialiang, Li, Kailong, Cai, Wenqing, Liu, Xin, Zhang, Yuannyu, Orkin, Stuart H., Xu, Jian, Yuan, Guo-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838163/
https://www.ncbi.nlm.nih.gov/pubmed/29507293
http://dx.doi.org/10.1038/s41467-018-03279-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838163/
https://www.ncbi.nlm.nih.gov/pubmed/29507293
http://dx.doi.org/10.1038/s41467-018-03279-9

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