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LPS-primed CD11b(+) leukocytes serve as an effective carrier of Shiga toxin 2 to cause hemolytic uremic syndrome in mice

Shiga toxin (Stx)-induced hemolytic uremic syndrome (HUS) is a life-threatening complication associated with Stx-producing Escherichia coli infection. One critical barrier of understanding HUS is how Stx transports from infected intestine to kidney to cause HUS. Passive dissemination seems unlikely,...

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Detalles Bibliográficos
Autores principales: Niu, Shuo, Paluszynski, John, Bian, Zhen, Shi, Lei, Kidder, Koby, Liu, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838166/
https://www.ncbi.nlm.nih.gov/pubmed/29507316
http://dx.doi.org/10.1038/s41598-018-22327-4