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Evaluation of promoter methylation status of MLH1 gene in Iranian patients with colorectal tumors and adenoma polyps

AIM: The aim of this study was to evaluate the methylation status of the promoter region of MLH1 gene in colorectal cancer (CRC) and its precursor lesions as well as elucidate its association with various clinicopathological characteristics among Iranian population. BACKGROUND: Epigenetic silencing...

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Detalles Bibliográficos
Autores principales: Zarandi, Ashkan, Irani, Shiva, Savabkar, Sanaz, Chaleshi, Vahid, Ghavideldarestani, Maryam, Mirfakhraie, Reza, Khodadoostan, Mahsa, Nazemalhosseini-Mojarad, Ehsan, Asadzadeh Aghdaei, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838190/
https://www.ncbi.nlm.nih.gov/pubmed/29511481