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Analysis of the oligomeric states of nucleophosmin using size exclusion chromatography

Nucleophosmin (NPM1) is a multifunctional phosphoprotein which plays important roles in diverse biological processes. NPM1 can form homo- or hetero-oligomers through its N-terminal region, and bind DNA and RNA through its C-terminal region. However, the monomer-oligomer distribution of NPM1, and the...

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Detalles Bibliográficos
Autores principales: Sakashita, Gyosuke, Kiyoi, Hitoshi, Naoe, Tomoki, Urano, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838202/
https://www.ncbi.nlm.nih.gov/pubmed/29507312
http://dx.doi.org/10.1038/s41598-018-22359-w