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Lonoctocog Alfa: A Review in Haemophilia A

Lonoctocog alfa (rVIII-SingleChain; Afstyla(®)) is a novel single-chain recombinant factor VIII (FVIII) molecule, with a truncated B-domain and the heavy and light chains covalently linked to form a stable and homogenous drug that binds with high affinity to von Willebrand factor (VWF). Intravenous...

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Detalles Bibliográficos
Autores principales: Al-Salama, Zaina T., Scott, Lesley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838207/
https://www.ncbi.nlm.nih.gov/pubmed/28900904
http://dx.doi.org/10.1007/s40265-017-0815-0