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Region-Specific Methylation Profiling in Acute Myeloid Leukemia

Alteration of DNA methylation level in cancer diseases leads to deregulation of gene expression—silencing of tumor suppressor genes and enhancing of protooncogenes. There are several tools devoted to the problem of identification of CpG sites' demethylation but majority of them focuses on singl...

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Detalles Bibliográficos
Autores principales: Cecotka, Agnieszka, Polanska, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838208/
https://www.ncbi.nlm.nih.gov/pubmed/29405013
http://dx.doi.org/10.1007/s12539-018-0285-4