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DNAJC5 facilitates USP19-dependent unconventional secretion of misfolded cytosolic proteins
Cell-to-cell transmission of misfolded proteins propagates proteotoxic stress in multicellular organisms when transmitted polypeptides serve as a seeding template to cause protein misfolding in recipient cells, but how misfolded proteins are released from cells to initiate this process is unclear. M...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838229/ https://www.ncbi.nlm.nih.gov/pubmed/29531792 http://dx.doi.org/10.1038/s41421-018-0012-7 |