Neutrophil extracellular trap-microparticle complexes enhance thrombin generation via the intrinsic pathway of coagulation in mice

Abdominal sepsis is associated with dysfunctional hemostasis. Thrombin generation (TG) is a rate-limiting step in systemic coagulation. Neutrophils can expell neutrophil extracellular traps (NETs) and/or microparticles (MPs) although their role in pathological coagulation remains elusive. Cecal liga...

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Detalles Bibliográficos
Autores principales: Wang, Yongzhi, Luo, Lingtao, Braun, Oscar Ö, Westman, Johannes, Madhi, Raed, Herwald, Heiko, Mörgelin, Matthias, Thorlacius, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838234/
https://www.ncbi.nlm.nih.gov/pubmed/29507382
http://dx.doi.org/10.1038/s41598-018-22156-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838234/
https://www.ncbi.nlm.nih.gov/pubmed/29507382
http://dx.doi.org/10.1038/s41598-018-22156-5

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