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Neutrophil extracellular trap-microparticle complexes enhance thrombin generation via the intrinsic pathway of coagulation in mice
Abdominal sepsis is associated with dysfunctional hemostasis. Thrombin generation (TG) is a rate-limiting step in systemic coagulation. Neutrophils can expell neutrophil extracellular traps (NETs) and/or microparticles (MPs) although their role in pathological coagulation remains elusive. Cecal liga...
Autores principales: | Wang, Yongzhi, Luo, Lingtao, Braun, Oscar Ö, Westman, Johannes, Madhi, Raed, Herwald, Heiko, Mörgelin, Matthias, Thorlacius, Henrik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838234/ https://www.ncbi.nlm.nih.gov/pubmed/29507382 http://dx.doi.org/10.1038/s41598-018-22156-5 |
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