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Genetic Variability in eIF2α Gene Is Associated with Islet β-Cell Function in the Development of Diabetes in a Chinese Han Population

AIMS: Protein kinase-like endoplasmic reticulum kinase (PERK)/eukaryotic translation initiation factor 2 alpha (eIF2α) pathway mutations lead to failure of β-cell function. The aim of this article was to assess the association between eIF2α and the risk of glucose metabolism abnormalities. METHODS:...

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Detalles Bibliográficos
Autores principales: Gu, Nan, Ma, Xiaowei, Zhang, Jianwei, Jin, Mengmeng, Feng, Nan, Deng, Ruifen, Bai, Ge, Zhang, Hong, Guo, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838474/
https://www.ncbi.nlm.nih.gov/pubmed/29675042
http://dx.doi.org/10.1155/2018/6590532