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Honokiol Ameliorates Myocardial Ischemia/Reperfusion Injury in Type 1 Diabetic Rats by Reducing Oxidative Stress and Apoptosis through Activating the SIRT1-Nrf2 Signaling Pathway

Reducing oxidative stress is a crucial therapeutic strategy for ameliorating diabetic myocardial ischemia/reperfusion (MI/R) injury. Honokiol (HKL) acts as an effective cardioprotective agent for its strong antioxidative activity. However, its roles and underlying mechanisms against MI/R injury in t...

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Detalles Bibliográficos
Autores principales: Zhang, Bin, Zhai, Mengen, Li, Buying, Liu, Zhenhua, Li, Kaifeng, Jiang, Liqing, Zhang, Meng, Yi, Wei, Yang, Jian, Yi, Dinghua, Liang, Hongliang, Jin, Zhenxiao, Duan, Weixun, Yu, Shiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838504/
https://www.ncbi.nlm.nih.gov/pubmed/29675132
http://dx.doi.org/10.1155/2018/3159801