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A High-fat and High-Cholesterol Diet Potentiates Oxidative Damage in Hippocampus of Mice Lacking Apolipoprotein E

OBJECTIVE: We examined genetic and dietary challenge on hippocampal oxidative damage. Mice expressing (ApoE+/+) or lacking apolipoprotein E (ApoE-/-) were maintained on a standard diet or a high fat /high cholesterol (challenge) diet for 11-31 weeks. Similar levels of oxidative species were observed...

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Detalles Bibliográficos
Autores principales: Guaraldi, Mary, Shea, Thomas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838635/
https://www.ncbi.nlm.nih.gov/pubmed/29541261
http://dx.doi.org/10.2174/1874205X01812010012