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Interleukin‐17 regulates matrix metalloproteinase activity in human pulmonary tuberculosis

Tuberculosis (TB) is characterized by extensive pulmonary matrix breakdown. Interleukin‐17 (IL‐17) is key in host defence in TB but its role in TB‐driven tissue damage is unknown. We investigated the hypothesis that respiratory stromal cell matrix metalloproteinase (MMP) production in TB is regulate...

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Detalles Bibliográficos
Autores principales: Singh, Shivani, Maniakis‐Grivas, George, Singh, Utpal K, Asher, Radha M, Mauri, Francesco, Elkington, Paul T, Friedland, Jon S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838784/
https://www.ncbi.nlm.nih.gov/pubmed/29210073
http://dx.doi.org/10.1002/path.5013