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NYX-2925 Is a Novel NMDA Receptor-Specific Spirocyclic-β-Lactam That Modulates Synaptic Plasticity Processes Associated with Learning and Memory

BACKGROUND: N-methyl-D-aspartate receptors are one member of a family of ionotropic glutamate receptors that play a pivotal role in synaptic plasticity processes associated with learning and have become attractive therapeutic targets for diseases such as depression, anxiety, schizophrenia, and neuro...

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Detalles Bibliográficos
Autores principales: Khan, M Amin, Houck, David R, Gross, Amanda L, Zhang, Xiao-lei, Cearley, Cassia, Madsen, Torsten M, Kroes, Roger A, Stanton, Patric K, Burgdorf, Jeffrey, Moskal, Joseph R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838819/
https://www.ncbi.nlm.nih.gov/pubmed/29099938
http://dx.doi.org/10.1093/ijnp/pyx096