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NYX-2925 Is a Novel NMDA Receptor-Specific Spirocyclic-β-Lactam That Modulates Synaptic Plasticity Processes Associated with Learning and Memory
BACKGROUND: N-methyl-D-aspartate receptors are one member of a family of ionotropic glutamate receptors that play a pivotal role in synaptic plasticity processes associated with learning and have become attractive therapeutic targets for diseases such as depression, anxiety, schizophrenia, and neuro...
Autores principales: | Khan, M Amin, Houck, David R, Gross, Amanda L, Zhang, Xiao-lei, Cearley, Cassia, Madsen, Torsten M, Kroes, Roger A, Stanton, Patric K, Burgdorf, Jeffrey, Moskal, Joseph R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838819/ https://www.ncbi.nlm.nih.gov/pubmed/29099938 http://dx.doi.org/10.1093/ijnp/pyx096 |
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