Cargando…

Crosstalk between VEGFR and other receptor tyrosine kinases for TKI therapy of metastatic renal cell carcinoma

Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cell carcinoma (RCC), and is frequently accompanied by the genetic features of von Hippel–Lindau (VHL) loss. VHL loss increases the expression of hypoxia-inducible factors (HIFs) and their targets, including epidermal growth...

Descripción completa

Detalles Bibliográficos
Autores principales: Lai, Yongchang, Zhao, Zhijian, Zeng, Tao, Liang, Xiongfa, Chen, Dong, Duan, Xiaolu, Zeng, Guohua, Wu, Wenqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838927/
https://www.ncbi.nlm.nih.gov/pubmed/29527128
http://dx.doi.org/10.1186/s12935-018-0530-2