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Reproducible proteomics sample preparation for single FFPE tissue slices using acid-labile surfactant and direct trypsinization
BACKGROUND: Proteomic analyses of clinical specimens often rely on human tissues preserved through formalin-fixation and paraffin embedding (FFPE). Minimal sample consumption is the key to preserve the integrity of pathological archives but also to deal with minimal invasive core biopsies. This has...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838928/ https://www.ncbi.nlm.nih.gov/pubmed/29527141 http://dx.doi.org/10.1186/s12014-018-9188-y |